Which body systems are primarily affected by cystic fibrosis?

Cystic fibrosis primarily affects the lungs and the digestive system due to a genetic mutation that disrupts the movement of chloride ions in and out of cells. This leads to the production of thick, sticky mucus that can clog the airways in the lungs, making it hard to breathe and increasing the risk of lung infections. In the digestive system, this thick mucus can block the pancreatic ducts, preventing digestive enzymes from reaching the intestines and leading to malabsorption of nutrients. Thus, individuals with cystic fibrosis frequently experience respiratory problems and difficulties with digestion, highlighting the significant impact on these two body systems.